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Tuesday, September 16, 2008

Gene fuels deadly prostate cancer - BBC News

A faulty factor closely associated with breast malignant neoplastic disease is also responsible for a particularly unsafe word form of prostate gland cancer, research have confirmed.

A University of Toronto squad establish prostate gland malignant neoplastic disease patients carrying the BRCA2 factor lived on norm for four old age after diagnosis.

The norm endurance clip for a adult male with prostate gland malignant neoplastic disease is 12 years.

Experts said the British Diary of Cancer survey emphasised the importance of early sensing and treatment.

It is of import that more than research is done in this country to guarantee that this grouping is targeted effectively

Dr Lesley WalkerCancer Research UK

Each twelvemonth around 35,000 new lawsuits of prostate gland malignant neoplastic disease are diagnosed in the UK, and around 10,000 work force decease from the disease

The up-to-the-minute survey - based on 301 patients - examined two closely related faulty genes, BRCA1 and BRCA2, both of which greatly increase a woman's hazard of breast cancer, and are linked to ovarian cancer.

Both factors cut mean endurance modern times in work force with prostate gland malignant neoplastic disease who carried them - for work force carrying BRCA1 the norm endurance clip was eight old age after diagnosis.

BRCA2 have already been linked to deathly prostate gland gland cancer, with an Icelandic survey recording an norm endurance clip among prostate malignant neoplastic disease patients carrying the factor of just 2.1 years.

The up-to-the-minute survey looks to corroborate that link.

Double whammy

Around one in 500 work force transport the faulty BRCA2 gene. They can be five modern times more likely than work force in the general population to develop prostate gland cancer.

Lead research worker Dr Steven Narod said: "We cognize that carrying a faulty BRCA2 factor additions a man's hazard of getting prostate gland gland cancer, and our survey shows that it also impacts how long he will last a diagnosing of the disease."

Dr Lesley Walker, of the charity Cancer Research UK, said: "Although lone a very little per centum of work force with prostate malignant neoplastic disease will transport a faulty BRCA2 gene, they're much more than likely to decease from the disease.

"It is of import that more than than research is done in this country to guarantee that this grouping is targeted effectively so malignant neoplastic disease is picked up at an early phase and, more importantly, that they are given the most appropriate treatment.

"Men with a strong household history of prostate gland or breast malignant neoplastic disease can see their general practitioner for advice."

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Monday, September 1, 2008

Mediterranean diet 'cuts cancer' - BBC News

Adopting just a couple of elements of the Mediterranean Sea diet could cut the hazard of malignant neoplastic disease by 12%, state scientists.

A survey of 26,000 Grecian people establish just using more than olive oil alone cut the hazard by 9%.

The diet, studies the British Diary of Cancer, also includes higher amounts of fruits, vegetables, cereals, and less redness meat.

A separate survey establish adding Brassica oleracea italica to repasts might assist work force vulnerable to prostate gland malignant neoplastic disease cut their risk.

It demoes there are a figure of things you tin do, and there is no 1 'superfood' that can halt you developing the disease

Sara HiomCancer Research UK

The Mediterranean Sea diet came under examination after research workers noticed less rates of unwellnesses such as as as bosom disease in states such as Kingdom Of Spain and Greece.

They noticed that people living there generally ate more than veggies and fish, less reddish meat, cooked in olive oil and drank moderate amounts of alcohol.

The up-to-the-minute survey is one of the biggest yet to look at the possible impact on malignant neoplastic disease of the assorted parts of this diet.

'No superfood'

Researchers from Harvard University University persuaded one thousands of Grecian people of assorted ages to enter their nutrient consumption over an eight-year-period.

Broccoli may assist ward off prostate gland cancer

Their attachment to the Mediterranean Sea diet was ranked using a scoring system, and the grouping with the worst mark compared with those who followed a couple of facets of the diet, and those who followed it the most closely.

The greatest consequence they establish - a 9% decrease in hazard - was achieved simply by eating more than "unsaturated" fats such as as olive oil.

But just two alterations - eating less redness meat, and more than peas, edible beans and lentils, cut the hazard of malignant neoplastic disease by 12%.

Dr Dimitrios Trichopoulos, who led the study, said: "Adjusting one's overall dietary wonts towards the traditional Mediterranean Sea form had an of import effect."

Sara Hiom, from Cancer Research UK, said the research highlighted the importance of a healthy balanced diet.

"It demoes there are a figure of things you tin do, and there is no 1 'superfood' that can halt you developing the disease."

Broccoli benefit

The other survey suggesting that nutrient had the powerfulness to forestall malignant neoplastic disease came from the Institute of Food Research in Norwich.

Scientists compared the personal effects of adding 400 grammes of Brassica oleracea italica or peas a hebdomad to the diet of work force at high hazard of prostate gland gland malignant neoplastic disease - and in the lawsuit of Brassica oleracea italica establish differences in the activity of factors in the prostate which other surveys have got linked to cancer.

Their determinations raised the possibility that broccoli, or other "cruciferous" vegetables, such as as Brassica oleracea botrytis and Bruxelles sprouts, could assist forestall or slow down the disease, particularly if the adult male had a peculiar factor discrepancy - GSTM1.

Professor Richard Mithen, who led the research, published in the Populace Library of Science journal, said: "Eating two or three parts of cruciferous veggies per week, and maybe a few more than if you miss the GSTM1 factor - should be encouraged."

Professor Karol Sikora, medical manager of CancerPartnersUK, said the survey was the first clip in a properly controlled clinical trial that Brassica oleracea italica had been shown to change the look of specific factors in the prostate secretory organ gland.

"Although the observation time period was too short and the Numbers too little to demo that the relative incidence of malignant neoplastic disease actually fell, it is the first clear presentation that Brassica oleracea italica and presumably other cruciferous veggies may well cut down malignant neoplastic disease risk."

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