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Friday, September 12, 2008

Researchers: Colon Cancer Vaccine on the Horizon

Researchers hope that a protein establish in the bowels could take to the find of a vaccine for colon cancer, Reuters reported Tuesday.

A survey published in the Diary of the National Cancer Institute elaborate how mice were immunized with the protein and subsequently contaminated with colon tumors.

These mice had fewer tumours spreading to the lung and liver than usual. Unvaccinated animate beings had an norm of 30 new tumours in the lungs and liver, compared to the vaccinated mice that had three new tumors, research workers said.

The vaccinated mice also lived longer, the research workers wrote.

Colon malignant neoplastic disease impacts 1.2 million people in the human race each twelvemonth and kills 130,000.

Adam Snook and Dr. George C. Scott Waldman of Seth Thomas Thomas Jefferson University in City Of Brotherly Love wanted to look at colon malignant neoplastic disease because the intestinal lining — a mucosal country — is protected from much of the immune system activity.

Some proteins from these immune-protected sites are active on tumour cells, they said.

Snook and Waldman looked specifically at guanylyl Degree Centigrade protein, or GCC protein, which is normally only active in the intestinal lining and in spreading colorectal malignant neoplastic disease cells.

Cancers of the caput and neck, lung, breast, vagina and vesica also get in the mucosa, so this attack could also work for them, they said.

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